Intelligence is the most powerful force in the world, and humans are increasingly losing out to computers in various intellectual pursuits. Can you take a pill that will make you smarter? If you could, would you? We would, and so would our guest Jesse Lawler, the host of the excellent podcast Smart Drug Smarts. We cover the gamut of currently available substances that are claimed to have the effect of enhancing intelligence. We discuss how current drugs and supplements on the market are not exactly silver bullet ‘smart’ pills but rather push us in one direction or another, with trade-offs. We also discuss some of the more speculative technology coming down the pike, and what might be the next big thing in nootropics.